PUBLICATIONS

Obesity has become a major pandemic in the United States and other countries and is a major burden to healthcare costs due to its co-morbidities including cardiovascular disease, type 2 diabetes, and cancer. More effective ways to treat and prevent obesity and its related co-morbidities is a dire need currently being addressed by biomedical and …

DNA Methylation at PON3 May Lead to Weight Loss in Humans Following a Hypocaloric Diet. Read More »

Autism rates have risen steadily in the past two decades, now affecting an estimated 1 in 54 children in the US. Efforts to better understand this condition and treat it effectively have risen, too. However, the underlying causes of autism spectrum disorder (ASD) remain unclear, and there is no known preventative measure or cure. But …

Epigenetic Biomarkers May Help Assess a Father’s Likelihood of Having an Autistic Child Read More »

Over the past few years, ketogenic diets have become one of the most popular weight loss tools out there. Numerous studies show ketogenic diets are effective for weight loss in obese and overweight individuals and if you do a quick social media search for “Ketogenic diet” or “Keto” you will find countless anecdotes that support …

How a Ketogenic Diet May Change Your Gene Expression Read More »

Noise-induced hearing loss (NIHL) affects about 40 million adults in the U.S aged 20-69 (1). As the name suggests, it is a loss of hearing due to loud noise exposure. The louder the noise and the more often a person is exposed to it, the more it harms their hearing. Although it is the second …

Epigenetics May Be Involved in Noise-Induced Hearing Loss Read More »

Tuberculosis (TB) may be one of the oldest and deadliest diseases in history, but it is still very much a threat to people all over the world. Despite the availability of effective treatments and efforts to control it, TB ranks among the top 10 deadliest infectious diseases today. Treatment usually includes a multiple drug course …

Epigenetics May Explain How Tuberculosis Develops Antibiotic Resistance Read More »

A new technique has been developed that is expected to advance our knowledge of numerous underlying biological processes, including those implicated in complex diseases like cancer. Using machine learning —a form of artificial intelligence— scientists can predict gene regulation at the cellular level – a process that, before now, has been nearly impossible to do …

Breakthrough Technique Calculates Gene Regulation at the Single-Cell Level Using Deep-Learning Read More »

Male infertility is a huge problem affecting nearly 1 in 10 men of reproductive age. This issue is occurring alongside observed reductions in sperm count in men over the last several decades. Although the reasons for these observations are not yet fully understood, environmental toxicants and poor diet could both be involved by adversely affecting …

Nut Consumption Improves Sperm Parameters and May Alter Epigenome Read More »

Aging is a fact of life that cannot be avoided. From the moment we are born, every part of us starts to age, and slowly over time, the cells and tissues in our bodies progressively decline in their ability to repair and restore themselves. Our eyes get hit even harder by this occurrence, especially nowadays, …

Reversing Vision Loss by Restoring Youthful Epigenetic Information Read More »

Obesity is currently a major healthcare concern in the United States and biomedical researchers are still working to untangle the complexity of the physiological changes that occur as a result of increased fat gain. Human beings have two major types of fat in their bodies which are white and brown adipose tissue (WAT and BAT, …

Epigenetic Regulator TET1 May Prevent Beiging of Fat Cells Read More »